Atlas of the Neuropathology of HIV Infection

HIV infection ultimately results in a wide variety of lesions in almost every organ of the body. The classification and diagnosis of these lesions are often difficult as they can appear in a variety of forms and are affected by other opportunistic pathogens characteristic of AIDS. This volume is a systematic, pictorial guide to the lesions which affect the central and peripheral nervous systems in particular. The pathological appearances of the lesions are correlated with radiological, ophthalmic and cytological information. The book also demonstrates the use of more sophisticated techniques such as immunocytochemistry, in situ hybridization and electron microscopic investigations in diagnosing and understanding the pathogenic mechanisms of these lesions. Although the later neurological complications of AIDS are covered comprehensively, the early neurological effects of HIV infection are also discussed. The full range of lesions is surveyed, including rare and unusual pathological features.Table of ContentPart 1 Topographic descriptions of the lesions: involvement of the brain; involvement of the spinal cord; - of the pituitary; - of the eye; CSF cytology; involvement of the peripheral nervous system; - of muscles. Part 2 Combination of pathological lesions due to different agents. Part 3 Variation of the lesions according to different factors.